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Overview
With the highest level of automation available in any cell sorter, the MA900 represents modern engineering that delivers both precision and simplicity. From intelligent sensors to guided workflows, the MA900’s automation transforms cell sorting into an easy-to-learn, easy-to-use process, empowering researchers to achieve their goals faster and more reliably.
The MA900 Cell Sorter offers intuitive operation, supporting up to 12 fluorescence parameters and 4-way sorting. Ideal for multi-parameter sorting and single-cell isolation, it is designed to enhance productivity and accuracy across a range of applications.
By combining ease of use with advanced, customizable controls, the MA900 software makes high-precision sorting accessible and is an ideal solution for labs focused on streamlined, reliable performance without a steep learning curve.
Product Highlights
Innovation in Benchtop Design
The MA900 brings advanced innovation to benchtop cell sorting, meeting the demands of most applications with support for up to 12 fluorescence parameters and 4-way sorting. At its core is a patented microfluidic chip–based architecture, paired with comprehensive fluidic controls and intelligent automation to simplify operation, reduce user subjectivity, and enhance reliability.
With up to 14 total parameters from four excitation lasers (405, 488, 561, and 638 nm) across two beam spots, the MA900 delivers exceptional flexibility. Freeform PMTs enable precise detection of 12 fluorescence and 2 scatter parameters for confident, high-quality data.
Automation is embedded throughout the workflow, with one-touch startup, QC, aseptic cleaning, and sort setup ensuring consistent alignment, accurate targeting, and rapid recovery from clogs. Wizard-based, customizable cleaning cycles further streamline maintenance and support aseptic sorting.
An intuitive software interface guides users through operation while offering advanced controls for customization - making the MA900 cell sorter easy to learn, efficient to use, and designed to keep the focus on biology rather than instrument complexity.
The compact footprint of the MA900 Cell Sorter makes it easy to incorporate into a variety of lab environments, even those with space constraints. This design helps maximize bench space, enabling labs to add the MA900 cell sorter alongside other laboratory instruments ensuring space efficiency.
Robust Fluidics
Central to the design of the MA900 Cell Sorter is a microfluidics chip that combines the flow cell and nozzle into one integrated unit. A range of chip sizes (70μm, 100μm, and 130μm) support sorting of a variety of cells from 0.5um to 25um in size.
Patented Precision
The MA900's microfluidic chip-based design is key to achieving high precision and reliability during sorting. Unlike traditional flow cytometers that rely on more complex fluidic paths, this chip-based design enables more controlled cell movement and reduces variability.
Microfluidic technology minimizes the chances of clogging and allows for seamless operation, which translates to less downtime and higher productivity in the lab.
Intuitive Operation
With advanced automation, the MA900 streamlines routine tasks such as alignment, cleaning, and maintenance, transforming them into effortless processes that maximize productivity in the lab. By eliminating much of the complexity and variability from cytometry workflows, the MA900 empowers laboratories to achieve greater precision and reproducibility while maintaining ease of operation.
This makes the MA900 exceptionally user-friendly, solution designed for the demands of modern research environments. Its intuitive software provides guided workflows with step‑by‑step instructions, simplifying critical processes including QC and calibration, experiment setup, and parameter selection for sorting into 4‑way tubes or plates
Sorting that adapts to your needs with default and custom sort modes as well as 4-way sorting
Once events are gated on plots, target cells can be sorted for further analysis. Sort mode, sort gates, and sort devices can be assigned using a simple dialog box. A choice of eight default and five custom sort modes is available to achieve the desired purity and yield of the sorted population. Sort devices supported include 2-way and 4-way tubes as well as 6-, 12-, 24-, 48-, 96-, and 384-well plates.
Experiment Settings
Experiments can be created by selecting a new template, a recent experiment, or a shared template (public) from the experiment window. If a new template is selected, the software guides you through choosing experiment settings such as sample groups, tubes, and pulse parameters for data acquisition. Once a template is selected or created, compensation data can be acquired easily by using the software-based compensation wizard. Alternatively, uncompensated populations can be adjusted using the drag and drop feature in the software.
Data Display and Using Gates
During acquisition, data is displayed on worksheets as dot plots and histograms. Events in the plots can be marked using gates. A variety of tools are provided to select, adjust, label, and measure statistics of target populations. Once acquired, data can be easily exported as FCS formats to use with third party analysis software.
Streamlined Workflows
Beyond experiment workflows, the MA900 also supports system maintenance and troubleshooting, ensuring smooth operation and minimizing downtime. This built‑in guidance enhances user confidence and operational efficiency - an invaluable advantage for laboratories with demanding schedules.
With one-touch startup, aseptic cleaning, and QC functions, the MA900 ensures streamlined experience for lab personnel. This minimizes the typical time spent on repetitive tasks and reduces setup times, allowing more focus on data analysis and experimental design.
Automated Setup
The MA900’s automated sort setup quickly and accurately configures sorting parameters, reducing the need for manual adjustments. This feature not only speeds up the workflow but also decreases the likelihood of setup errors, which is crucial for multi-parameter experiments. CoreFinder™ algorithm streamlines setup and automates chip alignment, laser delay, stream calibration, drop delay and side stream adjustment. Each chip can be set up at precise frequency, and the setup is robust and consistent across frequent chip exchanges over time.
Automated Fluid Sensing
The fluidics cart houses autoclavable sheath, deionized water, and waste tanks as well as tanks containing bleach and ethanol. Weighted sensors on the fluidics cart allow a real-time measurement of the fluid levels, which is displayed in the software.
Wizard-Driven Cleaning Cycle
Software guides the operation of default and custom fluidic system cleaning. Default cycles include cleaning with bleach or ethanol. Software guides you through each step of the selected cleaning cycle. Fluid is pumped from three cleaning tanks via a cleaning chip. The software also supports user-defined protocols for setting the time for cleaning. In addition, cleaning reminders can be set up by administrators for convenience.